Oral bug on world stage

Monday, June 22, 2015

 

The infamous oral pathogen Porphyromonas gingivalis now has its own international conference. PG2015 was held in London in June and five researchers from the Oral Health CRC were among the guests. 

It was the second conference dedicated to exploring growing understanding of the bug which is widely recognised as the 'ring leader' in establishing chronic periodontitis. It is also associated with a range of systemic diseases including cardiovascular and inflammatory diseases.

CEO of the Oral Health CRC, Melbourne Laureate Professor Eric Reynolds AO, was a co-convenor of the conference, alongside Koji Nakayama from Nagasaki University and Mike Curtis from the Queen Mary University of London.

"The conference was a unique opportunity to hear about research going on round the world into Porphyromonas gingivalis," said Professor Reynolds. "Advances in technology are providing us with increasing information about how this bacterium sustains itself and how it responds to treatment."

The Oral Health CRC is working with Sanofi Pasteur and CSL Limited on an immune based therapy targeting Porphyromonas gingivalis for the treatment of chronic periodontitis. 

Professor Reynolds' presentation at the conference outlined the promising findings of his research group in inducing an immune response against P. gingivalis and significantly reducing inflammation and alveolar bone loss.  Associate Professor Neil O'Brien-Simpson, also from the Oral Health CRC, spoke at the conference on the development of a saliva-based chairside diagnostice for the early detection of P. gingivalis

Professor Eric Reynolds and the University of Melbourne will host the next Porphyromonas gingivalis conference, to be held in Melbourne in May 2017.